SEH1L

Across TCGA patient cohorts, SEH1L protein abundance is significantly associated with the RNA expression of many other genes, with 12,590 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible SEH1L-associated genes across cancer lineages are COMP, PODN, and NEXN. Each is linked with SEH1L in more than 5 cancer types. Because this analysis shows association rather than direction, both SEH1L-to-partner and partner-to-SEH1L results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SEH1L versus COMP in OV, with a Pearson correlation of -0.31.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SEH1L→partner) and Y-score (partner→SEH1L) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	COMP →	-1.675	-0.166	.004	.009	3	6
CCRCC	PODN →	-1.096	-0.134	<.001	<.001	3	6
HNSC	NEXN →	-0.822	-0.117	<.001	.001	3	5
OV	FBN1 →	-1.086	-0.188	.002	<.001	3	5
GBM	GREM1 →	-1.297	-0.226	<.001	<.001	3	5
LSCC	MMP2 →	-1.082	-0.153	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,590 associations by consensus.

SEH1L vs COMP — OV

Explore this scatter interactively →