SEH1L

Across TCGA cell cohorts, SEH1L RNA expression is significantly associated with the go_rna of many other GO terms, with 4,685 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible SEH1L-associated GO terms across cancer lineages are Sister chromatid cohesion, RNA (guanine-N7)-methylation, and rRNA metabolic process. Each is linked with SEH1L in more than 16 cancer types. Because this analysis shows association rather than direction, both SEH1L-to-partner and partner-to-SEH1L results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Sister chromatid cohesion grouped by SEH1L-low versus SEH1L-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SEH1L→partner) and Y-score (partner→SEH1L) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Sister chromatid cohesion →	+0.149	+0.975	.002	.008	3	17
OESOPHAGUS	RNA (guanine-N7)-methylation →	+0.158	+0.958	.005	.004	2	17
BONE	rRNA metabolic process →	+0.140	+1.047	<.001	<.001	3	16
UPPER_AERODIGESTIVE_TRACT	Nuclear division →	+0.068	+0.987	.008	.002	3	16
BLOOD_Myeloma	Maturation of SSU-rRNA →	+0.129	+0.930	.004	.002	3	16
BONE	Ribosomal large subunit biogenesis →	+0.134	+0.804	<.001	<.001	2	17

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,685 associations by consensus.

Sister chromatid cohesion by SEH1L expression — BONE

Explore this box plot interactively →