SEH1L

mutation — cross-omics
Cross-omicsMUTATION → PROTEIN-RPPACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, SEH1L mutation is significantly associated with the total protein of many other genes, with 1 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible SEH1L-associated genes across cancer lineages are PCNA. Each is linked with SEH1L in more than 1 cancer types. Because this analysis shows association rather than direction, both SEH1L-to-partner and partner-to-SEH1L results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PCNA grouped by SEH1L-low versus SEH1L-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SEH1L→partner) and Y-score (partner→SEH1L) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LARGE_INTESTINEPCNA →+0.600+2.688<.001.04731
Each partner links to its Q-omics profile. Showing the 1 strongest of 1 associations by consensus.

PCNA by SEH1L expression — LARGE_INTESTINE

Box plot of PCNA in SEH1L-low vs SEH1L-high samples in LARGE_INTESTINE.

Explore this box plot interactively →

Exploration