SEC62-AS1

Across TCGA pan-cancer cohorts, SEC62-AS1 RNA is linked to patient survival in 20 of 34 cancer types, making it the most broadly survival-associated SEC62-AS1 data layer.

The strongest signal is observed in thyroid carcinoma (THCA), where higher SEC62-AS1 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated SEC62-AS1 expression acts as an unfavorable survival marker, although some lineages such as LUAD and HNSC show a favorable association.

THCA, LUAD, and HNSC are the cancer types where SEC62-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
THCA	OS	Quartile	II,III,IV	0.558	0.982	.002	57	view →
LUAD	OS	Median	All	0.847	0.727	.004	52	view →
HNSC	DFS	Median	II,III,IV	0.413	0.240	.004	21	view →
BLCA	DFS	Median	All	0.158	0.472	.003	18	view →
CHOL	DFS	Median	All	0.718	0.122	.001	16	view →
BRCA	OS	Tertile	III,IV	0.950	0.841	.012	16	view →
LIHC	DFS	Median	II,III,IV	0.248	0.400	.018	14	view →
READ	DFS	Tertile	IV	0.223	0.767	.013	13	view →
LAML	DFS	Tertile	All	0.461	0.255	.036	10	view →
LUSC	DFS	Tertile	III,IV	0.288	0.816	.015	10	view →
COAD	OS	Median	IV	0.769	0.528	.010	9	view →
SKCM	DFS	Median	IV	0.187	0.763	.006	6	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 20 lineages.

SEC62-AS1–THCA (OS)

Open the THCA breakdown →