SEC62-AS1

Across TCGA pan-cancer cohorts, SEC62-AS1 RNA differs between tumor and matched normal tissue in 10 of 18 cancer types tested, making tumor–normal expression one of SEC62-AS1’s most consistent transcriptional readouts.

The strongest signal is observed in bladder urothelial carcinoma (BLCA), where SEC62-AS1 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types SEC62-AS1 is over-expressed in tumor, although a few such as THCA and PAAD show the opposite, repressed pattern.

BLCA, THCA, and KIRC are the cancer types where SEC62-AS1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in SEC62-AS1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
BLCA	All	III,IV	+0.325	.037	5	view →
THCA	All	All	−0.326	.003	4	view →
KIRC	All	All	+0.155	.006	3	view →
PAAD	Male	All	−0.580	.007	2	view →
CHOL	All	All	+0.501	.011	2	view →
LUAD	Male	III,IV	−0.443	.017	2	view →
PRAD	All	All	+0.324	<.001	2	view →
LIHC	All	All	+0.115	.012	2	view →
STAD	All	II,III,IV	+0.314	.046	1	view →
LUSC	All	All	+0.296	.036	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 10 strongest of 10 lineages.

SEC62-AS1–BLCA

Open the BLCA breakdown →