SEC61G

Across TCGA patient cohorts, SEC61G RNA expression is significantly associated with the protein abundance of many other proteins, with 10,767 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible SEC61G-associated proteins across cancer lineages are EGFR, EGFR_T693, and P4HA2. Each is linked with SEC61G in more than 7 cancer types. Because this analysis shows association rather than direction, both SEC61G-to-partner and partner-to-SEC61G results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SEC61G versus EGFR in GBM, with a Pearson correlation of 0.67.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (SEC61G→partner) and Y-score (partner→SEC61G) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	EGFR →	+1.423	+2.457	<.001	<.001	3	8
PDAC	EGFR_T693 →	+0.914	+0.446	.001	<.001	3	7
CCRCC	P4HA2 →	+0.851	+0.475	<.001	<.001	3	6
BRCA	CYSLTR1_S326 →	-1.533	-0.722	.003	.002	3	6
BRCA	EGFR_S1064 →	+1.404	+0.879	<.001	<.001	3	6
HNSC	IL16 →	-0.515	-0.930	.002	.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,767 associations by consensus.

SEC61G vs EGFR — GBM

Explore this scatter interactively →