SEC61G

Across TCGA cell cohorts, SEC61G RNA expression is significantly associated with the go_rna of many other GO terms, with 3,463 significant associations in total. CNS shows the largest number of these associations.

The most reproducible SEC61G-associated GO terms across cancer lineages are Peptidyl-glutamic acid carboxylation, Protein carboxylation, and Positive regulation of protein exit from endoplasmic reticulum. Each is linked with SEC61G in more than 9 cancer types. Because this analysis shows association rather than direction, both SEC61G-to-partner and partner-to-SEC61G results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Peptidyl-glutamic acid carboxylation grouped by SEC61G-low versus SEC61G-high in URINARY_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SEC61G→partner) and Y-score (partner→SEC61G) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	Peptidyl-glutamic acid carboxylation →	+0.102	+0.860	.003	.001	3	10
URINARY_TRACT	Protein carboxylation →	+0.102	+0.860	.003	.001	3	10
LIVER	Positive regulation of protein exit from endoplasmic reticulum →	+0.156	+0.672	<.001	.004	3	9
BONE	Protein localization to early endosome →	+0.231	+0.758	<.001	<.001	3	9
SKIN	Cellular response to nitrogen levels →	+0.128	+0.747	<.001	.002	3	8
SOFT_TISSUE	Endoplasmic reticulum to Golgi vesicle-mediated transport →	+0.074	+0.739	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,463 associations by consensus.

Peptidyl-glutamic acid carboxylation by SEC61G expression — URINARY_TRACT

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