SEC61A2

Across TCGA patient cohorts, SEC61A2 RNA expression is significantly associated with the protein abundance of many other proteins, with 18,119 significant associations in total. GBM shows the largest number of these associations.

The most reproducible SEC61A2-associated proteins across cancer lineages are NUDT5, PHYKPL, and HNRNPLL. Each is linked with SEC61A2 in more than 4 cancer types. Because this analysis shows association rather than direction, both SEC61A2-to-partner and partner-to-SEC61A2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SEC61A2 versus NUDT5 in OV, with a Pearson correlation of 0.49.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (SEC61A2→partner) and Y-score (partner→SEC61A2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	NUDT5 →	+0.564	+0.617	<.001	<.001	3	5
LSCC	PHYKPL →	-0.420	-0.563	<.001	<.001	3	5
HNSC	HNRNPLL →	+0.283	+0.621	<.001	<.001	3	5
GBM	HDAC2 →	+0.315	+0.459	<.001	<.001	3	5
GBM	UPF2 →	+0.220	+0.702	<.001	<.001	3	4
LSCC	UPF3B →	+0.300	+0.731	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 18,119 associations by consensus.

SEC61A2 vs NUDT5 — OV

Explore this scatter interactively →