SEC24B-AS1

Across TCGA pan-cancer cohorts, SEC24B-AS1 RNA differs between tumor and matched normal tissue in 12 of 18 cancer types tested, making tumor–normal expression one of SEC24B-AS1’s most consistent transcriptional readouts.

The strongest signal is observed in liver hepatocellular carcinoma (LIHC), where SEC24B-AS1 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types SEC24B-AS1 is over-expressed in tumor, although a few such as THCA and BRCA show the opposite, repressed pattern.

LIHC, THCA, and BRCA are the cancer types where SEC24B-AS1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in SEC24B-AS1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
LIHC	Female	All	+0.231	<.001	9	view →
THCA	Male	All	−0.472	<.001	8	view →
BRCA	Female	All	−0.157	.009	6	view →
CHOL	Female	All	+1.083	<.001	5	view →
COAD	All	All	+0.221	.001	4	view →
BLCA	All	All	+0.215	.016	4	view →
STAD	All	All	+0.203	.001	4	view →
HNSC	Male	III,IV	+0.198	.010	4	view →
KICH	Female	All	−0.735	<.001	3	view →
KIRC	Male	III,IV	−0.202	.017	3	view →
LUSC	Male	III,IV	−0.380	.020	2	view →
LUAD	All	All	+0.185	.007	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 12 lineages.

SEC24B-AS1–LIHC

Open the LIHC breakdown →