SEC23A-AS1

Across TCGA pan-cancer cohorts, SEC23A-AS1 RNA differs between tumor and matched normal tissue in 3 of 18 cancer types tested, making tumor–normal expression one of SEC23A-AS1’s most consistent transcriptional readouts.

The strongest signal is observed in liver hepatocellular carcinoma (LIHC), where SEC23A-AS1 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types SEC23A-AS1 is over-expressed in tumor, although a few such as KIRP show the opposite, repressed pattern.

LIHC, KIRP, and PRAD are the cancer types where SEC23A-AS1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in SEC23A-AS1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
LIHC	All	All	+0.103	<.001	4	view →
KIRP	All	IV	−0.172	.002	2	view →
PRAD	All	All	+0.103	.030	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 3 strongest of 3 lineages.

SEC23A-AS1–LIHC

Open the LIHC breakdown →