SEC22B3P

Across TCGA pan-cancer cohorts, SEC22B3P RNA is linked to patient survival in 10 of 34 cancer types, making it the most broadly survival-associated SEC22B3P data layer.

The strongest signal is observed in cervical squamous cell carcinoma and endocervical adenocarcinoma (CESC), where higher SEC22B3P RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated SEC22B3P expression acts as an unfavorable survival marker, although some lineages such as GBM show a favorable association.

CESC, SKCM, and LIHC are the cancer types where SEC22B3P RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
CESC	DFS	Tertile	III,IV	0.053	0.729	<.001	54	view →
SKCM	OS	Tertile	III,IV	0.158	0.489	.001	42	view →
LIHC	OS	Tertile	All	0.598	0.802	.004	27	view →
READ	OS	Tertile	IV	0.334	0.918	<.001	27	view →
KICH	OS	Tertile	II,III,IV	0.216	0.838	.010	18	view →
GBM	DFS	Median	All	0.391	0.191	.003	18	view →
HNSC	OS	Tertile	III,IV	0.309	0.567	.012	18	view →
COAD	DFS	Tertile	III,IV	0.035	0.698	<.001	18	view →
PCPG	DFS	Tertile	All	0.080	0.857	.013	18	view →
OV	OS	Quartile	III,IV	0.252	0.331	.023	8	view →

Pink = unfavorable, green = favorable. Showing the 10 strongest of 10 lineages.

SEC22B3P–CESC (DFS)

Open the CESC breakdown →