SEC22B

Across TCGA patient cohorts, SEC22B RNA expression is significantly associated with the protein abundance of many other proteins, with 9,286 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible SEC22B-associated proteins across cancer lineages are DNAJC19, NUBPL, and SEC22B_S175. Each is linked with SEC22B in more than 3 cancer types. Because this analysis shows association rather than direction, both SEC22B-to-partner and partner-to-SEC22B results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SEC22B versus DNAJC19 in BRCA, with a Pearson correlation of -0.31.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (SEC22B→partner) and Y-score (partner→SEC22B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	DNAJC19 →	-0.370	-0.402	.005	.008	3	4
COAD	NUBPL →	-0.405	-0.510	<.001	<.001	3	4
LSCC	SEC22B_S175 →	+0.596	+0.700	<.001	<.001	3	4
OV	TRAP1 →	-0.490	-0.366	<.001	.001	3	4
OV	ISCA2 →	-0.426	-0.344	.001	.002	3	4
BRCA	MAPKAPK2 →	+0.348	+0.522	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,286 associations by consensus.

SEC22B vs DNAJC19 — BRCA

Explore this scatter interactively →