SEC16B

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, SEC16B protein abundance is significantly associated with the RNA expression of many other genes, with 3,802 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SEC16B-associated genes across cancer lineages are COL16A1, RNF122, and VSIR. Each is linked with SEC16B in more than 2 cancer types. Because this analysis shows association rather than direction, both SEC16B-to-partner and partner-to-SEC16B results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SEC16B versus COL16A1 in UCEC, with a Pearson correlation of 0.36.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SEC16B→partner) and Y-score (partner→SEC16B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECCOL16A1 →+1.802+0.565.001.00233
LUADRNF122 →+1.181+1.337.008.00333
UCECVSIR →+1.332+0.540.003.00432
LUADSPOCK2 →+1.447+1.121.001.00632
LUADSELPLG →+1.279+0.935<.001<.00132
UCECGNAI2 →+0.905+0.565.002.00232
Each partner links to its Q-omics profile. Showing the 6 strongest of 3,802 associations by consensus.

SEC16B vs COL16A1 — UCEC

Per-sample scatter of SEC16B vs COL16A1 in UCEC (Pearson r = 0.36).

Explore this scatter interactively →

Exploration