SEC16B

Across TCGA cell cohorts, SEC16B RNA expression is significantly associated with the go_rna of many other GO terms, with 4,288 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible SEC16B-associated GO terms across cancer lineages are Lymphocyte apoptotic process, Regulation of protein localization to membrane, and Regulation of protein localization to cell periphery. Each is linked with SEC16B in more than 11 cancer types. Because this analysis shows association rather than direction, both SEC16B-to-partner and partner-to-SEC16B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Lymphocyte apoptotic process grouped by SEC16B-low versus SEC16B-high in LIVER.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SEC16B→partner) and Y-score (partner→SEC16B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIVER	Lymphocyte apoptotic process →	+0.144	+1.780	.006	.008	2	12
OVARY	Regulation of protein localization to membrane →	+0.087	+1.036	<.001	<.001	3	11
OVARY	Regulation of protein localization to cell periphery →	+0.092	+0.916	<.001	<.001	3	11
SOFT_TISSUE	Antigen processing and presentation of exogenous peptide antigen via MHC class Ib →	+0.228	+0.797	<.001	<.001	3	10
OESOPHAGUS	Positive regulation of protein localization to plasma membrane →	+0.105	+0.774	<.001	.006	3	10
BREAST	Regulation of cytokine-mediated signaling pathway →	+0.072	+0.655	.001	.009	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,288 associations by consensus.

Lymphocyte apoptotic process by SEC16B expression — LIVER

Explore this box plot interactively →