Across TCGA cell cohorts, SEC14L6 mutation is significantly associated with the RNA expression of many other genes, with 3 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible SEC14L6-associated genes across cancer lineages are C16orf92, GAST, and GUCA2A. Each is linked with SEC14L6 in more than 1 cancer types. Because this analysis shows association rather than direction, both SEC14L6-to-partner and partner-to-SEC14L6 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SEC14L6→partner) and Y-score (partner→SEC14L6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	C16orf92 →	+0.041	+4.415	<.001	.007	3	1
SKIN	GAST →	+0.521	+4.095	.004	.009	3	1
SKIN	GUCA2A →	+0.070	+4.273	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

Exploration

SEC14L6 survival (RNA) · tumor vs normal (RNA) · all SEC14L6 data types