SEC14L5

Across TCGA patient cohorts, SEC14L5 protein abundance is significantly associated with the RNA expression of many other genes, with 650 significant associations in total. GBM shows the largest number of these associations.

The most reproducible SEC14L5-associated genes across cancer lineages are CDKN3, GINS1, and CTSH. Each is linked with SEC14L5 in more than 1 cancer types. Because this analysis shows association rather than direction, both SEC14L5-to-partner and partner-to-SEC14L5 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SEC14L5 versus CDKN3 in GBM, with a Pearson correlation of -0.90.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SEC14L5→partner) and Y-score (partner→SEC14L5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	CDKN3 →	-2.223	-2.470	<.001	.004	3	1
GBM	GINS1 →	-1.627	-2.469	.001	.004	3	1
GBM	CTSH →	+2.261	+2.660	<.001	<.001	3	1
GBM	LAPTM4B →	-1.366	-2.946	.002	.008	3	1
GBM	ARRDC2 →	+2.161	+2.660	.001	<.001	3	1
GBM	WDR91 →	+0.899	+2.660	.008	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 650 associations by consensus.

SEC14L5 vs CDKN3 — GBM

Explore this scatter interactively →