SEC11C

Across TCGA patient cohorts, SEC11C RNA expression is significantly associated with the protein abundance of many other proteins, with 12,144 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible SEC11C-associated proteins across cancer lineages are SEC23B, CRELD2, and SDF2L1. Each is linked with SEC11C in more than 8 cancer types. Because this analysis shows association rather than direction, both SEC11C-to-partner and partner-to-SEC11C results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SEC11C versus SEC23B in HNSC, with a Pearson correlation of 0.43.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (SEC11C→partner) and Y-score (partner→SEC11C) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	SEC23B →	+0.354	+0.977	<.001	<.001	3	9
LUAD	CRELD2 →	+0.524	+0.786	<.001	<.001	3	7
COAD	SDF2L1 →	+0.367	+0.684	<.001	<.001	3	6
GBM	CRTAP →	-0.488	-0.537	.003	<.001	3	6
LSCC	LMAN1 →	+0.405	+0.504	<.001	<.001	3	6
COAD	NUCB2 →	+0.631	+0.914	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,144 associations by consensus.

SEC11C vs SEC23B — HNSC

Explore this scatter interactively →