SEBOX

Across TCGA patient cohorts, SEBOX RNA expression is significantly associated with the go_rna of many other GO terms, with 6,468 significant associations in total. STAD shows the largest number of these associations.

The most reproducible SEBOX-associated GO terms across cancer lineages are Protein localization to vacuole, Nuclear-transcribed mRNA catabolic process, nonsense-mediated decay, and Obsolete regulation of histone modification. Each is linked with SEBOX in more than 15 cancer types. Because this analysis shows association rather than direction, both SEBOX-to-partner and partner-to-SEBOX results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Protein localization to vacuole grouped by SEBOX-low versus SEBOX-high in DLBC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SEBOX→partner) and Y-score (partner→SEBOX) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
DLBC	Protein localization to vacuole →	+0.058	+0.109	.001	<.001	3	16
ESCA	Nuclear-transcribed mRNA catabolic process, nonsense-mediated decay →	+0.054	+0.170	.002	<.001	3	16
ESCA	Obsolete regulation of histone modification →	+0.060	+0.245	.001	<.001	3	16
STAD	Alternative mRNA splicing, via spliceosome →	+0.051	+0.102	<.001	<.001	3	16
DLBC	Steroid hormone mediated signaling pathway →	+0.049	+0.112	<.001	<.001	3	16
DLBC	Vesicle localization →	+0.047	+0.091	.001	<.001	3	15

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,468 associations by consensus.

Protein localization to vacuole by SEBOX expression — DLBC

Explore this box plot interactively →