SDR9C7

Across TCGA patient cohorts, SDR9C7 mutation is significantly associated with the total protein of many other genes, with 17 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SDR9C7-associated genes across cancer lineages are Ku80, NF-kB-p65_pS536, and STAT3_pY705. Each is linked with SDR9C7 in more than 1 cancer types. Because this analysis shows association rather than direction, both SDR9C7-to-partner and partner-to-SDR9C7 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Ku80 grouped by SDR9C7-low versus SDR9C7-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SDR9C7→partner) and Y-score (partner→SDR9C7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Ku80 →	+0.367	+3.013	.007	.019	3	1
UCEC	NF-kB-p65_pS536 →	-0.519	-3.000	.048	.037	3	1
UCEC	STAT3_pY705 →	-0.615	-2.999	<.001	.035	3	1
UCEC	YB-1_pS102 →	-0.259	-3.000	.015	.037	3	1
UCEC	c-Met_pY1235 →	+0.094	+2.817	.028	.036	3	1
UCEC	ATM →	-0.669	-3.000	.010	.037	1	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 17 associations by consensus.

Ku80 by SDR9C7 expression — UCEC

Explore this box plot interactively →