SDR9C7

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, SDR9C7 mutation is significantly associated with the RNA expression of many other genes, with 5 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible SDR9C7-associated genes across cancer lineages are OR2W1, PNLIP, and OR10X1. Each is linked with SDR9C7 in more than 1 cancer types. Because this analysis shows association rather than direction, both SDR9C7-to-partner and partner-to-SDR9C7 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR2W1 grouped by SDR9C7-low versus SDR9C7-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SDR9C7→partner) and Y-score (partner→SDR9C7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BLOOD_LeukemiaOR2W1 →+0.022+5.539<.001.00332
BLOOD_LeukemiaPNLIP →+0.025+5.539<.001.00331
BLOOD_LeukemiaOR10X1 →+0.037+5.201<.001.00631
LARGE_INTESTINERAX2 →+0.077+3.196<.001.00731
LARGE_INTESTINEETDC →+0.615+4.415<.001<.00131
Each partner links to its Q-omics profile. Showing the 5 strongest of 5 associations by consensus.

OR2W1 by SDR9C7 expression — BLOOD_Leukemia

Box plot of OR2W1 in SDR9C7-low vs SDR9C7-high samples in BLOOD_Leukemia.

Explore this box plot interactively →

Exploration