Across TCGA patient cohorts, SDR42E1 mutation is significantly associated with the RNA expression of many other genes, with 2,425 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SDR42E1-associated genes across cancer lineages are IMMP1L, HOMER1, and VPS37A. Each is linked with SDR42E1 in more than 1 cancer types. Because this analysis shows association rather than direction, both SDR42E1-to-partner and partner-to-SDR42E1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SDR42E1→partner) and Y-score (partner→SDR42E1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	IMMP1L →	+0.525	+3.818	.001	<.001	3	2
UCEC	HOMER1 →	+0.723	+3.807	.004	<.001	3	2
UCEC	VPS37A →	+0.629	+2.711	.001	.003	3	2
UCEC	ST3GAL2 →	+0.519	+2.732	.002	.003	3	2
UCEC	CDC25C →	+0.618	+2.743	.009	.003	3	2
UCEC	NAE1 →	+0.651	+3.370	.001	.004	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,425 associations by consensus.

Exploration

SDR42E1 survival (RNA) · tumor vs normal (RNA) · all SDR42E1 data types