SDR39U1

Across TCGA patient cohorts, SDR39U1 mutation is significantly associated with the RNA expression of many other genes, with 897 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SDR39U1-associated genes across cancer lineages are TRAJ57, BPY2DP, and MIR425. Each is linked with SDR39U1 in more than 1 cancer types. Because this analysis shows association rather than direction, both SDR39U1-to-partner and partner-to-SDR39U1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TRAJ57 grouped by SDR39U1-low versus SDR39U1-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SDR39U1→partner) and Y-score (partner→SDR39U1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	TRAJ57 →	+1.212	+5.542	<.001	<.001	3	2
COAD	BPY2DP →	+0.293	+6.409	<.001	<.001	3	2
UCEC	MIR425 →	+0.389	+2.177	.001	.006	3	2
UCEC	ZNF519P4 →	+0.224	+2.714	<.001	.005	3	2
BRCA	MIR518F →	+0.396	+7.731	<.001	.009	3	2
BRCA	CYCSP48 →	+0.129	+8.471	<.001	.005	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 897 associations by consensus.

TRAJ57 by SDR39U1 expression — COAD

Explore this box plot interactively →