SDR39U1

Across TCGA pan-cancer cohorts, SDR39U1 RNA is linked to patient survival in 23 of 34 cancer types, making it the most broadly survival-associated SDR39U1 data layer compared with 3 for mutation status and 7 for mass-spec protein.

The strongest signal is observed in pancreatic adenocarcinoma (PAAD), where higher SDR39U1 RNA is associated with better disease-free survival. In most high-consensus cancer types, elevated SDR39U1 expression acts as an unfavorable survival marker, although some lineages such as PAAD and UCS show a favorable association.

PAAD, UVM, and UCS are the cancer types where SDR39U1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
PAAD	DFS	Quartile	All	0.457	0.193	.001	47	view →
UVM	OS	Quartile	III,IV	0.476	1.000	.006	46	view →
UCS	DFS	Median	IV	0.952	0.367	.001	36	view →
COAD	OS	Tertile	All	0.794	0.913	.008	35	view →
BRCA	OS	Quartile	III,IV	0.959	0.831	.002	35	view →
KIRP	DFS	Tertile	II,III,IV	1.000	0.374	.011	34	view →
MESO	OS	Quartile	All	0.675	0.394	<.001	33	view →
ESCA	DFS	Median	All	1.000	0.513	.006	21	view →
PRAD	DFS	Median	All	0.681	0.885	.001	18	view →
LUAD	DFS	Median	IV	0.212	0.777	.001	15	view →
ACC	DFS	Median	III,IV	0.584	0.109	.005	15	view →
OV	DFS	Tertile	IV	0.411	0.202	.011	12	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 23 lineages.

SDR39U1–PAAD (DFS)

Open the PAAD breakdown →