SDR39U1

Across TCGA cell cohorts, SDR39U1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,256 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible SDR39U1-associated GO terms across cancer lineages are Protein linear polyubiquitination, Positive regulation of intracellular estrogen receptor signaling pathway, and Regulation of DNA repair. Each is linked with SDR39U1 in more than 13 cancer types. Because this analysis shows association rather than direction, both SDR39U1-to-partner and partner-to-SDR39U1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Protein linear polyubiquitination grouped by SDR39U1-low versus SDR39U1-high in LUNG_NSCLC_LUAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SDR39U1→partner) and Y-score (partner→SDR39U1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	Protein linear polyubiquitination →	+0.139	+0.721	<.001	<.001	3	14
LUNG_SCLC	Positive regulation of intracellular estrogen receptor signaling pathway →	+0.155	+0.479	<.001	.001	3	14
UPPER_AERODIGESTIVE_TRACT	Regulation of DNA repair →	+0.070	+1.039	<.001	<.001	3	13
PANCREAS	Endothelial to hematopoietic transition →	+0.106	+0.558	<.001	.001	3	11
KIDNEY	Regulation of intracellular estrogen receptor signaling pathway →	+0.122	+0.808	<.001	<.001	3	11
BONE	Cell adhesion mediated by integrin →	-0.256	-0.734	.002	.006	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,256 associations by consensus.

Protein linear polyubiquitination by SDR39U1 expression — LUNG_NSCLC_LUAD

Explore this box plot interactively →