SDR16C6P

Mutation & survival
SurvivalMutationKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, SDR16C6P Mutation is linked to patient survival in 2 of 34 cancer types, making it a survival-associated SDR16C6P data layer compared with 18 for mass-spec protein.

The strongest signal is observed in esophageal carcinoma (ESCA), where higher SDR16C6P Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated SDR16C6P expression acts as an unfavorable survival marker.

ESCA and UCEC are the cancer types where SDR16C6P Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
ESCAOSMedianII,III,IV0.2280.706<.00124view →
UCECOSMedianIV0.2310.592.0366view →
Pink = unfavorable, green = favorable. Showing the 2 strongest of 2 lineages.

SDR16C6P–ESCA (OS)

Kaplan–Meier survival curve for SDR16C6P mutant vs wild-type samples in ESCA.

Open the ESCA breakdown →

Exploration