SDR16C6P

RNA — tumor vs normal
Tumor vs NormalRNABox plot · TCGA cohorts

Across TCGA pan-cancer cohorts, SDR16C6P RNA differs between tumor and matched normal tissue in 2 of 18 cancer types tested, making tumor–normal expression one of SDR16C6P’s most consistent transcriptional readouts.

The strongest signal is observed in lung squamous cell carcinoma (LUSC), where SDR16C6P RNA is repressed in tumor relative to normal tissue. In most cancer types SDR16C6P is over-expressed in tumor, although a few such as LUSC and LUAD show the opposite, repressed pattern.

LUSC and LUAD are the cancer types where SDR16C6P tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in SDR16C6P RNA (log2); positive values indicate higher expression in tumor. p-values are from the differential-expression test.
LineageGenderStageFold-changepSampling consensus
LUSCAllII,III,IV−0.067.0054view →
LUADMaleAll−0.079.0111view →
Pink = over-expressed in tumor, green = repressed in tumor. Showing the 2 strongest of 2 lineages.

SDR16C6P–LUSC

Tumor-vs-normal expression box plot for SDR16C6P RNA in LUSC.

Open the LUSC breakdown →

Exploration