SDR16C6P

Across TCGA patient cohorts, SDR16C6P mutation is significantly associated with the RNA expression of many other genes, with 2,727 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SDR16C6P-associated genes across cancer lineages are MIR4445, RNA5SP412, and RNA5SP138. Each is linked with SDR16C6P in more than 1 cancer types. Because this analysis shows association rather than direction, both SDR16C6P-to-partner and partner-to-SDR16C6P results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR4445 grouped by SDR16C6P-low versus SDR16C6P-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SDR16C6P→partner) and Y-score (partner→SDR16C6P) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	MIR4445 →	+0.153	+4.230	<.001	.004	3	2
UCEC	RNA5SP412 →	+0.618	+2.266	<.001	.001	3	2
UCEC	RNA5SP138 →	+0.376	+2.868	<.001	.009	3	2
UCEC	PWAR5 →	+0.563	+2.831	<.001	.001	3	1
UCEC	CCDC163 →	+0.632	+2.938	<.001	<.001	3	1
UCEC	RASSF1-AS1 →	+0.474	+3.628	<.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,727 associations by consensus.

MIR4445 by SDR16C6P expression — UCEC

Explore this box plot interactively →