SDR16C5

Across TCGA patient cohorts, SDR16C5 mutation is significantly associated with the RNA expression of many other genes, with 2,411 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible SDR16C5-associated genes across cancer lineages are OR10S1, RNU6-1067P, and SLC36A4. Each is linked with SDR16C5 in more than 1 cancer types. Because this analysis shows association rather than direction, both SDR16C5-to-partner and partner-to-SDR16C5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR10S1 grouped by SDR16C5-low versus SDR16C5-high in CESC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SDR16C5→partner) and Y-score (partner→SDR16C5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CESC	OR10S1 →	+0.042	+4.539	<.001	.008	3	2
CESC	RNU6-1067P →	+0.637	+5.569	<.001	.002	3	2
UCEC	SLC36A4 →	+0.618	+2.807	.007	.003	3	2
UCEC	MRPS23 →	+0.547	+3.928	.002	<.001	3	2
UCEC	LINC00471 →	+0.427	+3.459	.005	.005	3	2
UCEC	CLN8 →	+0.528	+3.928	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,411 associations by consensus.

OR10S1 by SDR16C5 expression — CESC

Explore this box plot interactively →