SDR16C5

Across TCGA cell cohorts, SDR16C5 mutation is significantly associated with the RNA expression of many other genes, with 10 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible SDR16C5-associated genes across cancer lineages are TCF21, TACR3, and OR6C76. Each is linked with SDR16C5 in more than 1 cancer types. Because this analysis shows association rather than direction, both SDR16C5-to-partner and partner-to-SDR16C5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TCF21 grouped by SDR16C5-low versus SDR16C5-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SDR16C5→partner) and Y-score (partner→SDR16C5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	TCF21 →	+0.011	+4.705	<.001	.003	3	1
BLOOD_Leukemia	TACR3 →	+0.038	+5.060	<.001	.001	3	1
BLOOD_Leukemia	OR6C76 →	+0.018	+4.539	<.001	.007	3	1
BLOOD_Leukemia	OR10T2 →	+0.707	+4.276	<.001	.007	3	1
BLOOD_Leukemia	VSTM2B →	+0.104	+4.874	<.001	.002	3	1
BLOOD_Leukemia	OR10R2 →	+1.349	+4.551	.004	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 10 associations by consensus.

TCF21 by SDR16C5 expression — BLOOD_Leukemia

Explore this box plot interactively →