SDK2

Across TCGA patient cohorts, SDK2 RNA expression is significantly associated with the protein abundance of many other proteins, with 9,189 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible SDK2-associated proteins across cancer lineages are MAP1B, MAP1B_S1154, and MAP1LC3A. Each is linked with SDK2 in more than 3 cancer types. Because this analysis shows association rather than direction, both SDK2-to-partner and partner-to-SDK2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SDK2 versus MAP1B in LSCC, with a Pearson correlation of 0.46.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (SDK2→partner) and Y-score (partner→SDK2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	MAP1B →	+0.870	+1.021	<.001	<.001	3	4
LSCC	MAP1B_S1154 →	+1.092	+1.460	<.001	<.001	3	4
PDAC	MAP1LC3A →	+0.708	+0.629	<.001	<.001	3	4
HNSC	ULK2_S528 →	+0.598	+2.088	.001	.004	3	3
LSCC	PCYT1B_S319 →	+0.945	+1.160	<.001	<.001	3	3
LSCC	PCYT1B_S346 →	+1.047	+1.097	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,189 associations by consensus.

SDK2 vs MAP1B — LSCC

Explore this scatter interactively →