SDK2

Across TCGA patient cohorts, SDK2 protein abundance is significantly associated with the RNA expression of many other genes, with 2,394 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SDK2-associated genes across cancer lineages are RAMP2, RGS22, and CDH24. Each is linked with SDK2 in more than 1 cancer types. Because this analysis shows association rather than direction, both SDK2-to-partner and partner-to-SDK2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SDK2 versus RAMP2 in PDAC, with a Pearson correlation of 0.68.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SDK2→partner) and Y-score (partner→SDK2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PDAC	RAMP2 →	+0.805	+1.551	.001	.008	3	2
BRCA	RGS22 →	+1.845	+0.484	.002	.008	3	2
UCEC	CDH24 →	-0.788	-0.565	.007	<.001	3	2
LSCC	CGN →	-0.929	-0.377	<.001	<.001	3	2
UCEC	INTS7 →	-0.714	-0.567	.007	<.001	3	2
UCEC	UBAP2L →	-0.311	-0.334	.002	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,394 associations by consensus.

SDK2 vs RAMP2 — PDAC

Explore this scatter interactively →