SDF4

Across TCGA patient cohorts, SDF4 protein abundance is significantly associated with the RNA expression of many other genes, with 12,937 significant associations in total. COAD shows the largest number of these associations.

The most reproducible SDF4-associated genes across cancer lineages are AGR2, TSPAN1, and UBXN1. Each is linked with SDF4 in more than 4 cancer types. Because this analysis shows association rather than direction, both SDF4-to-partner and partner-to-SDF4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SDF4 versus AGR2 in BRCA, with a Pearson correlation of 0.29.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SDF4→partner) and Y-score (partner→SDF4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	AGR2 →	+2.558	+0.304	.004	.004	3	5
LUAD	TSPAN1 →	+1.702	+0.310	<.001	<.001	3	5
GBM	UBXN1 →	-0.356	-0.383	.001	.004	3	5
LSCC	BICD2 →	-0.579	-0.210	.002	.007	3	5
LSCC	MSH2-OT1 →	-0.762	-0.239	.002	.002	3	5
GBM	REC8 →	-0.579	-0.311	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,937 associations by consensus.

SDF4 vs AGR2 — BRCA

Explore this scatter interactively →