SDF2L1

Across TCGA patient cohorts, SDF2L1 protein abundance is significantly associated with the RNA expression of many other genes, with 19,776 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible SDF2L1-associated genes across cancer lineages are SLAMF7, XBP1, and MZB1. Each is linked with SDF2L1 in more than 7 cancer types. Because this analysis shows association rather than direction, both SDF2L1-to-partner and partner-to-SDF2L1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SDF2L1 versus SLAMF7 in OV, with a Pearson correlation of 0.46.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SDF2L1→partner) and Y-score (partner→SDF2L1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	SLAMF7 →	+1.405	+0.440	<.001	<.001	3	8
HNSC	XBP1 →	+0.866	+0.339	<.001	<.001	3	7
BRCA	MZB1 →	+1.760	+0.392	<.001	<.001	3	7
OV	IGKV3-11 →	+2.617	+0.337	<.001	<.001	3	7
BRCA	IGKV1-9 →	+2.544	+0.364	<.001	<.001	3	7
OV	JCHAIN →	+2.046	+0.289	<.001	.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 19,776 associations by consensus.

SDF2L1 vs SLAMF7 — OV

Explore this scatter interactively →