SDF2L1

Across TCGA cell cohorts, SDF2L1 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,518 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible SDF2L1-associated GO terms across cancer lineages are Symbiont-mediated disruption of host cellular anatomical structure, Symbiont-mediated disruption of host anatomical structure, and GDP-mannose metabolic process. Each is linked with SDF2L1 in more than 12 cancer types. Because this analysis shows association rather than direction, both SDF2L1-to-partner and partner-to-SDF2L1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Symbiont-mediated disruption of host cellular anatomical structure grouped by SDF2L1-low versus SDF2L1-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SDF2L1→partner) and Y-score (partner→SDF2L1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Symbiont-mediated disruption of host cellular anatomical structure →	+0.143	+1.047	<.001	.005	3	13
UPPER_AERODIGESTIVE_TRACT	Symbiont-mediated disruption of host anatomical structure →	+0.143	+1.047	<.001	.005	3	13
SOFT_TISSUE	GDP-mannose metabolic process →	+0.146	+1.381	<.001	<.001	3	12
LARGE_INTESTINE	Replication-born double-strand break repair via sister chromatid exchange →	-0.084	-0.791	.004	.002	3	10
CNS	Negative regulation of macrophage chemotaxis →	+0.256	+1.490	<.001	<.001	3	10
UPPER_AERODIGESTIVE_TRACT	GDP-mannose biosynthetic process →	+0.135	+0.893	<.001	<.001	2	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,518 associations by consensus.

Symbiont-mediated disruption of host cellular anatomical structure by SDF2L1 expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →