SDCCAG8

Across TCGA cell cohorts, SDCCAG8 mutation is significantly associated with the RNA expression of many other genes, with 12 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible SDCCAG8-associated genes across cancer lineages are HOXD1, SH3GL3, and C1orf146. Each is linked with SDCCAG8 in more than 1 cancer types. Because this analysis shows association rather than direction, both SDCCAG8-to-partner and partner-to-SDCCAG8 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, HOXD1 grouped by SDCCAG8-low versus SDCCAG8-high in BLOOD_Lymphoma.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SDCCAG8→partner) and Y-score (partner→SDCCAG8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	HOXD1 →	+0.144	+4.485	.004	.001	3	1
BLOOD_Lymphoma	SH3GL3 →	+0.071	+3.554	<.001	.007	3	1
BLOOD_Lymphoma	C1orf146 →	+0.065	+3.459	<.001	.004	3	1
LUNG_NSCLC_LUAD	GJA8 →	+0.743	+4.734	<.001	.002	3	1
LUNG_NSCLC_LUAD	OR10K1 →	+0.006	+4.947	<.001	.001	3	1
CNS	ETDC →	+0.985	+5.754	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 12 associations by consensus.

HOXD1 by SDCCAG8 expression — BLOOD_Lymphoma

Explore this box plot interactively →