SDCBP2

Across TCGA pan-cancer cohorts, SDCBP2 mass-spec protein is linked to patient survival in 4 of 34 cancer types, making it a survival-associated SDCBP2 data layer compared with 17 for mass-spec protein and 3 for mutation status.

The strongest signal is observed in lung adenocarcinoma (LUAD), where higher SDCBP2 mass-spec protein is associated with worse overall survival. In most high-consensus cancer types, elevated SDCBP2 expression acts as an unfavorable survival marker, although some lineages such as HNSC and UCEC show a favorable association.

LUAD, HNSC, and UCEC are the cancer types where SDCBP2 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUAD	OS	Tertile	III,IV	0.175	1.000	.001	34	view →
HNSC	DFS	Median	All	0.886	0.303	.007	27	view →
UCEC	OS	Median	All	1.000	0.930	.019	16	view →
PDAC	DFS	Tertile	IV	0.224	0.777	.024	3	view →

Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

SDCBP2–LUAD (OS)

Open the LUAD breakdown →