SDCBP2

Across TCGA cell cohorts, SDCBP2 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,702 significant associations in total. PANCREAS shows the largest number of these associations.

The most reproducible SDCBP2-associated GO terms across cancer lineages are Intracellular receptor signaling pathway, Cellular response to steroid hormone stimulus, and Positive regulation of ruffle assembly. Each is linked with SDCBP2 in more than 12 cancer types. Because this analysis shows association rather than direction, both SDCBP2-to-partner and partner-to-SDCBP2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Intracellular receptor signaling pathway grouped by SDCBP2-low versus SDCBP2-high in BREAST.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SDCBP2→partner) and Y-score (partner→SDCBP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	Intracellular receptor signaling pathway →	+0.052	+2.301	<.001	<.001	3	13
UPPER_AERODIGESTIVE_TRACT	Cellular response to steroid hormone stimulus →	+0.085	+1.827	<.001	<.001	3	13
LUNG_NSCLC_LUAD	Positive regulation of ruffle assembly →	+0.150	+2.292	<.001	<.001	3	12
LUNG_NSCLC_LUSC	Small GTPase-mediated signal transduction →	+0.057	+1.922	.002	.001	3	12
URINARY_TRACT	Positive regulation of iron ion transport →	+1.837	+1.576	<.001	.002	3	11
URINARY_TRACT	Positive regulation of iron ion transmembrane transport →	+1.837	+1.576	<.001	.002	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,702 associations by consensus.

Intracellular receptor signaling pathway by SDCBP2 expression — BREAST

Explore this box plot interactively →