SDCBP

Across TCGA pan-cancer cohorts, SDCBP mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated SDCBP data layer compared with 25 for mass-spec protein and 1 for mutation status.

The strongest signal is observed in clear cell renal cell carcinoma (CCRCC), where higher SDCBP mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated SDCBP expression acts as an unfavorable survival marker, although some lineages such as UCEC and HNSC show a favorable association.

CCRCC, PDAC, and LUAD are the cancer types where SDCBP mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
CCRCC	DFS	Median	III,IV	0.105	0.928	.003	24	view →
PDAC	OS	Median	All	0.730	0.912	.017	4	view →
LUAD	DFS	Tertile	III,IV	0.280	0.800	.024	4	view →
UCEC	DFS	Quartile	All	0.958	0.781	.030	4	view →
HNSC	DFS	Tertile	IV	0.883	0.555	.035	2	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

SDCBP–CCRCC (DFS)

Open the CCRCC breakdown →