SDCBP

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, SDCBP protein abundance is significantly associated with the RNA expression of many other genes, with 10,047 significant associations in total. GBM shows the largest number of these associations.

The most reproducible SDCBP-associated genes across cancer lineages are LAPTM5, LRRC25, and CD33. Each is linked with SDCBP in more than 5 cancer types. Because this analysis shows association rather than direction, both SDCBP-to-partner and partner-to-SDCBP results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SDCBP versus LAPTM5 in OV, with a Pearson correlation of 0.30.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SDCBP→partner) and Y-score (partner→SDCBP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
OVLAPTM5 →+0.739+0.183.003.00626
OVLRRC25 →+0.689+0.217.008.00235
GBMCD33 →+0.606+0.258<.001<.00135
GBMNCF2 →+0.740+0.192<.001<.00135
GBMG0S2 →+1.851+0.230<.001.00235
GBMBCL2A1 →+1.828+0.356<.001<.00135
Each partner links to its Q-omics profile. Showing the 6 strongest of 10,047 associations by consensus.

SDCBP vs LAPTM5 — OV

Per-sample scatter of SDCBP vs LAPTM5 in OV (Pearson r = 0.30).

Explore this scatter interactively →

Exploration