SDCBP

Across TCGA cell cohorts, SDCBP RNA expression is significantly associated with the go_rna of many other GO terms, with 4,803 significant associations in total. BREAST shows the largest number of these associations.

The most reproducible SDCBP-associated GO terms across cancer lineages are Negative regulation of protein localization to centrosome, Regulation of L-glutamate import across plasma membrane, and Regulation of Fc receptor mediated stimulatory signaling pathway. Each is linked with SDCBP in more than 12 cancer types. Because this analysis shows association rather than direction, both SDCBP-to-partner and partner-to-SDCBP results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of protein localization to centrosome grouped by SDCBP-low versus SDCBP-high in LUNG_SCLC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SDCBP→partner) and Y-score (partner→SDCBP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	Negative regulation of protein localization to centrosome →	+0.155	+1.056	.002	.001	2	13
LIVER	Regulation of L-glutamate import across plasma membrane →	+0.274	+1.797	<.001	<.001	3	11
LUNG_NSCLC_LUSC	Regulation of Fc receptor mediated stimulatory signaling pathway →	+0.155	+1.174	<.001	<.001	3	11
LIVER	Intestinal lipid absorption →	+0.365	+1.573	.002	.004	3	11
BONE	Synaptic vesicle lumen acidification →	+0.141	+1.242	.002	.004	3	10
BREAST	Regulation of macrophage fusion →	+0.147	+1.138	.004	.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,803 associations by consensus.

Negative regulation of protein localization to centrosome by SDCBP expression — LUNG_SCLC

Explore this box plot interactively →