SCYL3

Across TCGA patient cohorts, SCYL3 protein abundance is significantly associated with the RNA expression of many other genes, with 7,256 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible SCYL3-associated genes across cancer lineages are FMO5, MPC2, and C9orf152. Each is linked with SCYL3 in more than 3 cancer types. Because this analysis shows association rather than direction, both SCYL3-to-partner and partner-to-SCYL3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SCYL3 versus FMO5 in BRCA, with a Pearson correlation of 0.29.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SCYL3→partner) and Y-score (partner→SCYL3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	FMO5 →	+1.334	+0.323	<.001	<.001	3	4
UCEC	MPC2 →	+0.698	+0.376	<.001	.002	3	4
BRCA	C9orf152 →	+1.749	+0.290	<.001	<.001	3	4
LUAD	RELT →	-0.634	-0.343	<.001	<.001	3	4
UCEC	TREM1 →	-0.848	-0.410	<.001	<.001	3	4
UCEC	SNX25P1 →	+0.742	+0.300	<.001	.002	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,256 associations by consensus.

SCYL3 vs FMO5 — BRCA

Explore this scatter interactively →