SCYL1

Across TCGA patient cohorts, SCYL1 protein abundance is significantly associated with the RNA expression of many other genes, with 11,009 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible SCYL1-associated genes across cancer lineages are FAM89B, SNHG7, and C11orf24. Each is linked with SCYL1 in more than 3 cancer types. Because this analysis shows association rather than direction, both SCYL1-to-partner and partner-to-SCYL1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SCYL1 versus FAM89B in BRCA, with a Pearson correlation of 0.30.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SCYL1→partner) and Y-score (partner→SCYL1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	FAM89B →	+0.409	+0.226	.005	.009	3	4
CCRCC	SNHG7 →	-0.817	-0.190	<.001	<.001	3	4
OV	C11orf24 →	+0.546	+0.193	<.001	<.001	3	4
OV	CFL1 →	+0.380	+0.232	<.001	<.001	3	4
LUAD	ZNRD2 →	+0.500	+0.219	<.001	<.001	3	4
LSCC	JAG1 →	-0.953	-0.223	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,009 associations by consensus.

SCYL1 vs FAM89B — BRCA

Explore this scatter interactively →