SCYL1

Across TCGA cell cohorts, SCYL1 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,613 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible SCYL1-associated GO terms across cancer lineages are Retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum, Positive regulation of anaphase-promoting complex-dependent catabolic process, and Negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway. Each is linked with SCYL1 in more than 11 cancer types. Because this analysis shows association rather than direction, both SCYL1-to-partner and partner-to-SCYL1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum grouped by SCYL1-low versus SCYL1-high in SOFT_TISSUE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SCYL1→partner) and Y-score (partner→SCYL1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	Retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum →	+0.079	+0.644	<.001	<.001	3	11
OVARY	Positive regulation of anaphase-promoting complex-dependent catabolic process →	+0.107	+0.549	<.001	<.001	2	12
BONE	Negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway →	+0.182	+0.598	<.001	.009	3	11
BONE	Vacuole organization →	+0.060	+0.624	.001	<.001	3	10
STOMACH	Intermembrane lipid transfer →	+0.110	+0.608	.001	.004	3	10
SKIN	Actin filament depolymerization →	+0.158	+0.563	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,613 associations by consensus.

Retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum by SCYL1 expression — SOFT_TISSUE

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