SCX

Across TCGA cell cohorts, SCX RNA expression is significantly associated with the go_rna of many other GO terms, with 4,449 significant associations in total. UPPER_AERODIGESTIVE_TRACT shows the largest number of these associations.

The most reproducible SCX-associated GO terms across cancer lineages are Negative regulation of myoblast fusion, Negative regulation of syncytium formation by plasma membrane fusion, and Cilium-dependent cell motility. Each is linked with SCX in more than 13 cancer types. Because this analysis shows association rather than direction, both SCX-to-partner and partner-to-SCX results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of myoblast fusion grouped by SCX-low versus SCX-high in OESOPHAGUS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SCX→partner) and Y-score (partner→SCX) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	Negative regulation of myoblast fusion →	+0.150	+1.098	.005	.001	3	14
OESOPHAGUS	Negative regulation of syncytium formation by plasma membrane fusion →	+0.149	+1.098	.005	.001	3	14
OESOPHAGUS	Cilium-dependent cell motility →	-0.109	-1.275	.001	<.001	3	14
OESOPHAGUS	Cilium movement involved in cell motility →	-0.125	-1.327	<.001	<.001	3	14
OESOPHAGUS	Cilium or flagellum-dependent cell motility →	-0.109	-1.275	.001	<.001	3	14
UPPER_AERODIGESTIVE_TRACT	Positive regulation of gastrulation →	-0.272	-1.182	.001	.004	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,449 associations by consensus.

Negative regulation of myoblast fusion by SCX expression — OESOPHAGUS

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