SCUBE3

Across TCGA patient cohorts, SCUBE3 RNA expression is significantly associated with the protein abundance of many other proteins, with 14,247 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible SCUBE3-associated proteins across cancer lineages are ISLR, LMCD1, and LMO7_S194. Each is linked with SCUBE3 in more than 4 cancer types. Because this analysis shows association rather than direction, both SCUBE3-to-partner and partner-to-SCUBE3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, SCUBE3 versus ISLR in CCRCC, with a Pearson correlation of 0.43.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (SCUBE3→partner) and Y-score (partner→SCUBE3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CCRCC	ISLR →	+0.787	+0.679	<.001	<.001	3	5
OV	LMCD1 →	+0.590	+0.783	<.001	.001	3	5
HNSC	LMO7_S194 →	+0.522	+0.806	<.001	<.001	3	5
HNSC	MFAP2 →	+0.680	+0.844	<.001	.001	3	5
CCRCC	DPYSL3 →	+0.580	+0.677	<.001	<.001	3	5
CCRCC	EFEMP2 →	+0.660	+0.487	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,247 associations by consensus.

SCUBE3 vs ISLR — CCRCC

Explore this scatter interactively →