SCUBE2

Across TCGA cell cohorts, SCUBE2 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,410 significant associations in total. BONE shows the largest number of these associations.

The most reproducible SCUBE2-associated GO terms across cancer lineages are Regulation of macroautophagy, Organelle transport along microtubule, and Regulation of cell-substrate junction assembly. Each is linked with SCUBE2 in more than 9 cancer types. Because this analysis shows association rather than direction, both SCUBE2-to-partner and partner-to-SCUBE2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of macroautophagy grouped by SCUBE2-low versus SCUBE2-high in STOMACH.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SCUBE2→partner) and Y-score (partner→SCUBE2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	Regulation of macroautophagy →	+0.075	+0.731	.002	.007	3	10
SKIN	Organelle transport along microtubule →	+0.044	+1.396	<.001	<.001	3	9
BONE	Regulation of cell-substrate junction assembly →	+0.155	+0.613	.001	.004	3	9
BONE	Endosomal transport →	+0.070	+0.826	.005	.001	3	9
BONE	Regulation of focal adhesion assembly →	+0.155	+0.613	.001	.004	3	9
STOMACH	Macroautophagy →	+0.083	+0.751	<.001	.004	2	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,410 associations by consensus.

Regulation of macroautophagy by SCUBE2 expression — STOMACH

Explore this box plot interactively →