SCRT1

Across TCGA patient cohorts, SCRT1 mutation is significantly associated with the RNA expression of many other genes, with 2,334 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SCRT1-associated genes across cancer lineages are RNU6-97P, SNORD127, and IGKV1-37. Each is linked with SCRT1 in more than 1 cancer types. Because this analysis shows association rather than direction, both SCRT1-to-partner and partner-to-SCRT1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-97P grouped by SCRT1-low versus SCRT1-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SCRT1→partner) and Y-score (partner→SCRT1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	RNU6-97P →	+0.609	+3.951	.005	.003	3	2
UCEC	SNORD127 →	+0.497	+1.879	<.001	.009	3	2
UCEC	IGKV1-37 →	+0.155	+2.582	<.001	.001	3	2
UCEC	CHURC1-FNTB →	+0.042	+2.289	.009	.001	3	2
UCEC	NDUFAF2P1 →	+0.700	+3.467	<.001	.002	3	1
BLCA	MIR4465 →	+0.728	+7.640	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,334 associations by consensus.

RNU6-97P by SCRT1 expression — COAD

Explore this box plot interactively →