SCRN3

Across TCGA cell cohorts, SCRN3 mutation is significantly associated with the RNA expression of many other genes, with 7 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible SCRN3-associated genes across cancer lineages are PCARE, NEUROD4, and PRSS54. Each is linked with SCRN3 in more than 1 cancer types. Because this analysis shows association rather than direction, both SCRN3-to-partner and partner-to-SCRN3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PCARE grouped by SCRN3-low versus SCRN3-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SCRN3→partner) and Y-score (partner→SCRN3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	PCARE →	+0.042	+5.201	<.001	.006	3	1
LUNG_NSCLC_LUAD	NEUROD4 →	+0.069	+3.215	<.001	.007	3	1
LARGE_INTESTINE	PRSS54 →	+0.038	+3.345	<.001	.007	3	1
LARGE_INTESTINE	ENPP6 →	+0.039	+4.115	<.001	.001	3	1
LARGE_INTESTINE	OR10A4 →	+0.061	+3.938	<.001	.002	3	1
LARGE_INTESTINE	OR4F21 →	+0.120	+3.878	.002	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 7 associations by consensus.

PCARE by SCRN3 expression — BLOOD_Leukemia

Explore this box plot interactively →