SCRG1

Across TCGA cell cohorts, SCRG1 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,451 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible SCRG1-associated GO terms across cancer lineages are Modulation of microtubule cytoskeleton involved in cerebral cortex radial glia guided migration, DNA synthesis involved in DNA replication, and Eosinophil differentiation. Each is linked with SCRG1 in more than 5 cancer types. Because this analysis shows association rather than direction, both SCRG1-to-partner and partner-to-SCRG1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Modulation of microtubule cytoskeleton involved in cerebral cortex radial glia guided migration grouped by SCRG1-low versus SCRG1-high in SKIN.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (SCRG1→partner) and Y-score (partner→SCRG1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	Modulation of microtubule cytoskeleton involved in cerebral cortex radial glia guided migration →	+0.138	+1.685	<.001	<.001	3	6
LUNG_SCLC	DNA synthesis involved in DNA replication →	+0.082	+0.062	.002	.004	3	5
BLOOD_Leukemia	Eosinophil differentiation →	-0.374	-0.022	.002	.007	3	5
BLOOD_Leukemia	[2Fe-2S] cluster assembly →	-0.087	-0.034	<.001	<.001	3	5
LUNG_SCLC	Translesion synthesis →	+0.082	+0.058	.001	.008	3	4
SKIN	Mesenchyme development →	+0.043	+1.684	.001	.002	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,451 associations by consensus.

Modulation of microtubule cytoskeleton involved in cerebral cortex radial glia guided migration by SCRG1 expression — SKIN

Explore this box plot interactively →