SCP2D1

Across TCGA patient cohorts, SCP2D1 mutation is significantly associated with the RNA expression of many other genes, with 917 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible SCP2D1-associated genes across cancer lineages are RNU6-370P, GTF2E2, and PNP. Each is linked with SCP2D1 in more than 1 cancer types. Because this analysis shows association rather than direction, both SCP2D1-to-partner and partner-to-SCP2D1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-370P grouped by SCP2D1-low versus SCP2D1-high in LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (SCP2D1→partner) and Y-score (partner→SCP2D1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	RNU6-370P →	+0.522	+5.410	<.001	.005	3	2
UCEC	GTF2E2 →	+0.590	+3.376	<.001	.004	3	2
UCEC	PNP →	+1.055	+3.387	<.001	.004	3	2
UCEC	RNA5SP379 →	+0.730	+2.747	<.001	<.001	3	2
UCEC	SNHG21 →	+0.712	+3.483	<.001	.002	3	2
UCEC	RNA5SP408 →	+0.328	+3.017	.002	.003	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 917 associations by consensus.

RNU6-370P by SCP2D1 expression — LUAD

Explore this box plot interactively →